The ES 300 includes both in-dash CD and cassette players. Automatic Sound Levelizer (ASL) adjusts volume up or down in response to ambient noise. In addition, an in-dash 6-CD changer is available with the Premium and Luxury Packages on ES 300, while a premium Mark Levinson audio system with 7 channels and 240 watts, is offered with the Luxury Package on ES 300.
Additional standard luxury features include a multi-information display with trip computer, Homelink garage door opener, and electrochromic auto-dimming rearview and sideview mirrors. A compass is integrated into the rearview mirror. Power windows on all four doors feature one-touch up/down control with pinch protection. Two more features adopted from the LS 430 include water-repellent front door glass and four-door courtesy lamps that illuminate the ground and doorsill areas.